TrypTag.org: from images to discoveries using genome-wide protein localisation in Trypanosoma brucei.

Sunter, Jack D; Dean, Samuel; Wheeler, Richard John

Sunter, Jack D; Dean, Samuel; Wheeler, Richard John.

Afiliación

Sunter JD; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK. Electronic address: jsunter@brookes.ac.uk.
Dean S; Warwick Medical School, University of Warwick, Coventry, UK. Electronic address: samuel.dean@warwick.ac.uk.
Wheeler RJ; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: richard.wheeler@ndm.ac.uk.

Trends Parasitol ; 39(5): 328-331, 2023 05.

Article en En | MEDLINE | ID: mdl-36925446

ABSTRACT

ABSTRACT

TrypTag was a 4-year project to tag the N- and C-termini of almost all Trypanosoma brucei proteins with a fluorescent protein and record the subcellular localisation through images and manual annotation. We highlight the new routes to cell biological discovery this transformative resource is enabling for parasitologists and cell biologists.

Asunto(s)

Trypanosoma brucei brucei; Trypanosoma brucei brucei/genética; Trypanosoma brucei brucei/metabolismo; Proteínas Protozoarias/genética; Proteínas Protozoarias/metabolismo; Transporte de Proteínas

Palabras clave

high-throughput imaging; kinetoplastid; molecular cell biology; trypanosome

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trypanosoma brucei brucei Idioma: En Revista: Trends Parasitol Asunto de la revista: PARASITOLOGIA Año: 2023 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google