Updates of placental macrophages: Origins, molecular markers, functions, and related diseases.
J Reprod Immunol
; 157: 103942, 2023 06.
Article
en En
| MEDLINE
| ID: mdl-36989681
ABSTRACT
Placental macrophages are highly heterogeneous cells with differential phenotypes and functions defined by differential origins and modulated by the changing placental environment. During pregnancy, placental macrophages play a critical role in embryo implantation, placenta formation and homeostasis, fetal development and parturition. This review summarizes recent findings on the cellular origin of placental macrophages, and provide a comprehensive description of their phenotypes, corresponding molecular markers and functions in human placenta. Finally, alterations of placental macrophages in pregnancy-related diseases are discussed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Placenta
/
Complicaciones del Embarazo
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
J Reprod Immunol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Alemania