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Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design.
La, Chanel C; Smith, Stephanie A; Vappala, Sreeparna; Adili, Reheman; Luke, Catherine E; Abbina, Srinivas; Luo, Haiming D; Chafeeva, Irina; Drayton, Matthew; Creagh, Louise A; de Guadalupe Jaraquemada-Peláez, Maria; Rhoads, Nicole; Kalathottukaren, Manu Thomas; Henke, Peter K; Straus, Suzana K; Du, Caigan; Conway, Edward M; Holinstat, Michael; Haynes, Charles A; Morrissey, James H; Kizhakkedathu, Jayachandran N.
Afiliación
  • La CC; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Smith SA; Department of Chemistry, University of British Columbia, Vancouver, BC, Canada.
  • Vappala S; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Adili R; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Luke CE; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Abbina S; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Luo HD; Bloodworks Research Institute, 1551 Eastlake Avenue E.; Ste. 100, Seattle, WA, 98102, USA.
  • Chafeeva I; Department of Surgery, Section of Vascular Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Drayton M; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Creagh LA; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • de Guadalupe Jaraquemada-Peláez M; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Rhoads N; Department of Chemistry, University of British Columbia, Vancouver, BC, Canada.
  • Kalathottukaren MT; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Henke PK; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Straus SK; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
  • Du C; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Conway EM; Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC, Canada.
  • Holinstat M; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
  • Haynes CA; Department of Chemistry, University of British Columbia, Vancouver, BC, Canada.
  • Morrissey JH; Bloodworks Research Institute, 1551 Eastlake Avenue E.; Ste.100, Seattle, WA, 98102, USA.
  • Kizhakkedathu JN; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Nat Commun ; 14(1): 2177, 2023 04 26.
Article en En | MEDLINE | ID: mdl-37100783
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Trombosis / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Trombosis / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Canadá