Occupational exposure to veterinary antibiotics: Pharmacokinetics of enrofloxacin in humans after dermal, inhalation and oral uptake - A clinical study.

Bluemlein, Katharina; Nowak, Norman; Ellinghusen, Birthe; Gerling, Susanne; Badorrek, Philipp; Hansen, Tanja; Hohlfeld, Jens M; Paul, Roland; Schuchardt, Sven

Bluemlein, Katharina; Nowak, Norman; Ellinghusen, Birthe; Gerling, Susanne; Badorrek, Philipp; Hansen, Tanja; Hohlfeld, Jens M; Paul, Roland; Schuchardt, Sven.

Afiliación

Bluemlein K; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Nowak N; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Ellinghusen B; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Gerling S; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Badorrek P; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Hansen T; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
Hohlfeld JM; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany; Department of Respiratory Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany; German Centre of Lung Research (DZL-BREATH), Hannover, Germany.
Paul R; Bundesanstalt für Arbeitsschutz und Arbeitsmedizin Gruppe 4.2 - Medizinischer Arbeitsschutz, Biomonitoring, Nöldnerstraße 40/42, 10317 Berlin, Germany.
Schuchardt S; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany. Electronic address: sven.schuchardt@item.fraunhofer.de.

Environ Toxicol Pharmacol ; 100: 104139, 2023 Jun.

Article en En | MEDLINE | ID: mdl-37142072

Asunto(s)

Antibacterianos; Exposición Profesional; Humanos; Ciprofloxacina; Estudios Cruzados; Enrofloxacina

Palabras clave

Dermal; Enrofloxacin; Inhalation; Oral; PBPK model; Pharmacokinetic

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 12_ODS3_hazardous_contamination Problema de salud: 12_occupational_exposures Asunto principal: Exposición Profesional / Antibacterianos Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Environ Toxicol Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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