Commercial and novel anticoagulant ECMO coatings: a review.
J Mater Chem B
; 11(22): 4832-4841, 2023 06 07.
Article
en En
| MEDLINE
| ID: mdl-37183615
ABSTRACT
Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and anticoagulation systems in a patient, leading to adverse consequences, such as bleeding and thrombosis. To address this problem, anticoagulation coatings have been developed for use in ECMO circuits. This article reviews commonly used commercial and novel anticoagulant coatings developed in recent years and proposes a new classification of coatings based on the current state. While commercial coatings have been used clinically for decades, this review focuses on comparing the effectiveness and stability of coatings to support clinical selections. Furthermore, novel anticoagulation coatings often involve complex mechanisms and elaborate design strategies, and this review summarises representative studies on mainstream anticoagulation coatings to provide a point of reference for future studies.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trombosis
/
Oxigenación por Membrana Extracorpórea
Límite:
Humans
Idioma:
En
Revista:
J Mater Chem B
Año:
2023
Tipo del documento:
Article
País de afiliación:
China