Identification of SARS-CoV-2 PLpro and 3CLpro human proteome substrates using substrate phage display coupled with protein network analysis.

Zhao, Kai; Li, Yini; Guo, Mengzhun; Ma, Lijia; Dang, Bobo

Zhao, Kai; Li, Yini; Guo, Mengzhun; Ma, Lijia; Dang, Bobo.

Afiliación

Zhao K; College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine,
Li Y; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China; Institute of Biology, Westlake Institute for Ad
Guo M; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China; Institute of Biology, Westlake Institute for Ad
Ma L; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China; Institute of Biology, Westlake Institute for Ad
Dang B; College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine,

J Biol Chem ; 299(6): 104831, 2023 06.

Article en En | MEDLINE | ID: mdl-37201587

Asunto(s)

COVID-19; SARS-CoV-2; Proteasas Virales; Humanos; Péptido Hidrolasas/metabolismo; Proteoma; SARS-CoV-2/enzimología; SARS-CoV-2/metabolismo

Palabras clave

NGS; SARS-CoV-2; cadherin; phage display; protease; substrate specificity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteasas Virales / SARS-CoV-2 / COVID-19 Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article

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