Significant Association of Cutavirus With Parapsoriasis en Plaques: High Prevalence Both in Skin Swab and Biopsy Samples.

Mohanraj, Ushanandini; Konttinen, Tuomas; Salava, Alexander; Väkevä, Liisa; Ranki, Annamari; Söderlund-Venermo, Maria

Mohanraj, Ushanandini; Konttinen, Tuomas; Salava, Alexander; Väkevä, Liisa; Ranki, Annamari; Söderlund-Venermo, Maria.

Afiliación

Mohanraj U; Department of Virology, University of Helsinki, Helsinki, Finland.
Konttinen T; Department of Virology, University of Helsinki, Helsinki, Finland.
Salava A; Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Väkevä L; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Ranki A; Department of Dermatology, Allergology, and Venereology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Söderlund-Venermo M; Department of Dermatology, Allergology, and Venereology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

Clin Infect Dis ; 77(7): 987-990, 2023 10 05.

Article en En | MEDLINE | ID: mdl-37234048

RESUMEN

Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin swabs of parapsoriasis patients (6/13; 46.2%) versus those of healthy adults (1/51; 1.96%). Eight patients (8/12; 66.7%) had CuV DNA in biopsied skin, and 4 developed CTCL.

Asunto(s)

Linfoma Cutáneo de Células T; Parapsoriasis; Neoplasias Cutáneas; Adulto; Humanos; Neoplasias Cutáneas/patología; Prevalencia; Parapsoriasis/genética; Parapsoriasis/patología; ADN; Biopsia

Palabras clave

cutaneous T-cell lymphoma; disease association; in situ hybridization; parapsoriasis; protoparvovirus

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Parapsoriasis / Neoplasias Cutáneas / Linfoma Cutáneo de Células T Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article País de afiliación: Finlandia

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