Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ.

Chen, Siyu; Vogt, Alex; Lee, Linda; Naila, Tasmin; McKeown, Ryan; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan

Chen, Siyu; Vogt, Alex; Lee, Linda; Naila, Tasmin; McKeown, Ryan; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan.

Afiliación

Chen S; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
Vogt A; Interdisciplinary Biological Sciences Program, Northwestern University. Evanston, IL, USA.
Lee L; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
Naila T; Interdisciplinary Biological Sciences Program, Northwestern University. Evanston, IL, USA.
McKeown R; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre and Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Tomkinson AE; Department of Internal Medicine and Molecular Genetics and Microbiology and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM, USA.
Lees-Miller SP; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
He Y; Interdisciplinary Biological Sciences Program, Northwestern University. Evanston, IL, USA.

Sci Adv ; 9(22): eadg2838, 2023 06 02.

Article en En | MEDLINE | ID: mdl-37256947

Asunto(s)

Reparación del ADN por Unión de Extremidades; Proteína Quinasa Activada por ADN; Proteína Quinasa Activada por ADN/metabolismo; Microscopía por Crioelectrón; Roturas del ADN de Doble Cadena; ADN/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína Quinasa Activada por ADN / Reparación del ADN por Unión de Extremidades Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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