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Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor.
Colombo, Sophie; Reddy, Haritha P; Petri, Sabrina; Williams, Damian J; Shalomov, Boris; Dhindsa, Ryan S; Gelfman, Sahar; Krizay, Daniel; Bera, Amal K; Yang, Mu; Peng, Yueqing; Makinson, Christopher D; Boland, Michael J; Frankel, Wayne N; Goldstein, David B; Dascal, Nathan.
Afiliación
  • Colombo S; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Reddy HP; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Petri S; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
  • Williams DJ; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Shalomov B; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Dhindsa RS; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Gelfman S; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Krizay D; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Bera AK; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Yang M; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
  • Peng Y; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Makinson CD; Mouse NeuroBehavior Core Facility, Columbia University Irving Medical Center, New York, NY, United States.
  • Boland MJ; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Frankel WN; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, United States.
  • Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, United States.
  • Dascal N; Department of Neurology, Columbia University Irving Medical Center, New York, NY, United States.
Front Cell Neurosci ; 17: 1175895, 2023.
Article en En | MEDLINE | ID: mdl-37275776
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_geracao_evidencia_conhecimento Idioma: En Revista: Front Cell Neurosci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_geracao_evidencia_conhecimento Idioma: En Revista: Front Cell Neurosci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos