Early decrease of blood myeloid-derived suppressor cells during checkpoint inhibition is a favorable biomarker in metastatic melanoma.

Gaißler, Andrea; Bochem, Jonas; Spreuer, Janine; Ottmann, Shannon; Martens, Alexander; Amaral, Teresa; Wagner, Nikolaus Benjamin; Claassen, Manfred; Meier, Friedegund; Terheyden, Patrick; Garbe, Claus; Eigentler, Thomas; Weide, Benjamin; Pawelec, Graham; Wistuba-Hamprecht, Kilian

Gaißler, Andrea; Bochem, Jonas; Spreuer, Janine; Ottmann, Shannon; Martens, Alexander; Amaral, Teresa; Wagner, Nikolaus Benjamin; Claassen, Manfred; Meier, Friedegund; Terheyden, Patrick; Garbe, Claus; Eigentler, Thomas; Weide, Benjamin; Pawelec, Graham; Wistuba-Hamprecht, Kilian.

Afiliación

Gaißler A; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Bochem J; Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Spreuer J; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Ottmann S; Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Martens A; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Amaral T; Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Wagner NB; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Claassen M; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Meier F; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Terheyden P; Cluster of Excellence iFIT (EXC 2180) "Image Guided and Functionally Instructed Tumor Therapies", Tübingen, Germany.
Garbe C; Department of Dermatology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Eigentler T; Department of Dermatology, Venereology and Allergology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.
Weide B; Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Pawelec G; Department of Computer Science, Eberhard Karls University of Tübingen, Tübingen, Germany.
Wistuba-Hamprecht K; Skin Cancer Center at the University Cancer Centre and National Center for Tumor Diseases Dresden; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

J Immunother Cancer ; 11(6)2023 06.

Article en En | MEDLINE | ID: mdl-37286306

Asunto(s)

Melanoma; Células Supresoras de Origen Mieloide; Humanos; Melanoma/patología; Biomarcadores; Resultado del Tratamiento; Citometría de Flujo

Palabras clave

T-lymphocytes; biomarkers, tumor; immunotherapy; melanoma; myeloid-derived suppressor cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 Problema de salud: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Células Supresoras de Origen Mieloide / Melanoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Immunother Cancer Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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