Isobavachalcone inhibits RANKL-induced osteoclastogenesis via miR-193-3p/NF-&#954;B/NFATc1 signaling pathway in BMMs cells.

Liu, Xin; Xu, Xiaosa; Li, Jinping; Shi, Liying; Zeng, Ying; Tang, Siyuan; Liu, Wei; Jia, Lujuan; Li, Yuhong; Zhang, Jie

Isobavachalcone inhibits RANKL-induced osteoclastogenesis via miR-193-3p/NF-κB/NFATc1 signaling pathway in BMMs cells.

Liu, Xin; Xu, Xiaosa; Li, Jinping; Shi, Liying; Zeng, Ying; Tang, Siyuan; Liu, Wei; Jia, Lujuan; Li, Yuhong; Zhang, Jie.

Afiliación

Liu X; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.
Xu X; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.
Li J; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.
Shi L; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Central South University, Chang Sha, Hunan, China.
Zeng Y; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.
Tang S; Department of Cardiovascular Medicine, The First Hospital of Hunan University of Traditional Chinese Medicine, Chang Sha, Hunan, China.
Liu W; Department of Community Nursing, Central South University, Changsha, Hunan, China.
Jia L; Department of Community Nursing, Central South University, Changsha, Hunan, China.
Li Y; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.
Zhang J; Department of Pharmachemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Chang Sha, Hunan, China.

Biosci Biotechnol Biochem ; 87(9): 960-971, 2023 Aug 23.

Article en En | MEDLINE | ID: mdl-37291698

Asunto(s)

Resorción Ósea; MicroARNs; Osteoporosis; Humanos; FN-kappa B/metabolismo; Osteogénesis; Ligando RANK/farmacología; Ligando RANK/metabolismo; Transducción de Señal; Osteoclastos; Resorción Ósea/tratamiento farmacológico; Resorción Ósea/genética; Resorción Ósea/metabolismo; Osteoporosis/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Diferenciación Celular; Factores de Transcripción NFATC/metabolismo

Palabras clave

NF-κB; RANKL; isobavachalcone; miR-193-3p; osteoclast

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Resorción Ósea / MicroARNs Límite: Humans Idioma: En Revista: Biosci Biotechnol Biochem Asunto de la revista: BIOQUIMICA / BIOTECNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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