Regulation of the CRISPR-Cas12a system by methylation and demethylation of guide RNA.

Hu, Zhian; Sun, Ao; Yang, Jinlei; Naz, Gul; Sun, Gongwei; Li, Zhengping; Gogo Liu, Jun-Jie; Zhang, Sichun; Zhang, Xinrong

Hu, Zhian; Sun, Ao; Yang, Jinlei; Naz, Gul; Sun, Gongwei; Li, Zhengping; Gogo Liu, Jun-Jie; Zhang, Sichun; Zhang, Xinrong.

Afiliación

Hu Z; Beijing Key Laboratory for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing 30 Xueyuan Road, Haidian District Beijing 100083 P. R. China.
Sun A; Department of Chemistry, Tsinghua University Beijing 100084 P. R. China xrzhang@mail.tsinghua.edu.cn sczhang@mail.tsinghua.edu.cn.
Yang J; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University Beijing 100084 P. R. China junjiegogoliu@mail.tsinghua.edu.cn.
Naz G; Department of Chemistry, Tsinghua University Beijing 100084 P. R. China xrzhang@mail.tsinghua.edu.cn sczhang@mail.tsinghua.edu.cn.
Sun G; Department of Chemistry, Tsinghua University Beijing 100084 P. R. China xrzhang@mail.tsinghua.edu.cn sczhang@mail.tsinghua.edu.cn.
Li Z; Department of Chemistry, Tsinghua University Beijing 100084 P. R. China xrzhang@mail.tsinghua.edu.cn sczhang@mail.tsinghua.edu.cn.
Gogo Liu JJ; Beijing Key Laboratory for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing 30 Xueyuan Road, Haidian District Beijing 100083 P. R. China.
Zhang S; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University Beijing 100084 P. R. China junjiegogoliu@mail.tsinghua.edu.cn.
Zhang X; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University Beijing 100084 P. R. China.

Chem Sci ; 14(22): 5945-5955, 2023 Jun 07.

Article en En | MEDLINE | ID: mdl-37293662

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2023 Tipo del documento: Article