Re-recognition of innate immune memory as an integrated multidimensional concept.
Microbiol Immunol
; 67(8): 355-364, 2023 Aug.
Article
en En
| MEDLINE
| ID: mdl-37311618
ABSTRACT
In the past decade, the concept of immunological memory, which has long been considered a phenomenon observed in the adaptive immunity of vertebrates, has been extended to the innate immune system of various organisms. This de novo immunological memory is mainly called "innate immune memory", "immune priming", or "trained immunity" and has received increased attention because of its potential for clinical and agricultural applications. However, research on different species, especially invertebrates and vertebrates, has caused controversy regarding this concept. Here we discuss the current studies focusing on this immunological memory and summarize several mechanisms underlying it. We propose "innate immune memory" as a multidimensional concept as an integration between the seemingly different immunological phenomena.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inmunidad Innata
/
Memoria Inmunológica
Límite:
Animals
Idioma:
En
Revista:
Microbiol Immunol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Japón