Multisystem inflammatory syndrome in children: an evolving understanding of a syndrome amid the inflammatory continuum.
Minerva Pediatr (Torino)
; 2023 Jun 16.
Article
en En
| MEDLINE
| ID: mdl-37335186
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a rare hyperinflammatory and immunosuppressed condition affecting children exposed to COVID-19. MIS-C has been associated with an over-exaggerated innate and adaptive immune response characterized by a 'selective' cytokine production and T cell suppression. As COVID-19 information has evolved, the knowledge and field surrounding MIS-C is ever evolving. Thus, a comprehensive clinical review that concisely presents current literature findings regarding common clinical presentations and comparisons with similar conditions, associations with the COVID-19 vaccine effects and relevant epigenetic markers and evaluates treatment and long-term outcomes to help guide future studies is needed and provided.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Minerva Pediatr (Torino)
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos