Identification of 58 novel HLA alleles identified in Chinese individuals by next-generation sequencing.
HLA
; 102(3): 343-347, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37376846
ABSTRACT
HLA genes are the most polymorphic in the human genome. High resolution HLA typing from 13,870 bone marrow donors in Hong Kong was obtained using Next-generation sequencing (NGS) technology. Among the 67 novel alleles identified, official HLA allele names of 50 novel class I alleles (HLA-A, -B, -C) and 8 novel class II alleles (HLA-DRB1, -DQB1) were assigned by the World Health Organization (WHO) Nomenclature Committee for Factors of the HLA System.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
Problema de salud:
2_cobertura_universal
Asunto principal:
Pueblos del Este de Asia
/
Antígenos de Histocompatibilidad
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
HLA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China