Optical coherence tomography angiography findings in pediatric patients with graves ophthalmopathy.
Int Ophthalmol
; 43(10): 3609-3614, 2023 Oct.
Article
en En
| MEDLINE
| ID: mdl-37392258
ABSTRACT
PURPOSE:
The aim of this study was to evaluate peripapillary, macular microvascular structure, and retinal nerve fiber layer (RNFL) thickness profile in children with Graves Ophthalmopathy (GO). MATERIAL ANDMETHODS:
Thirty-six eyes of 18 children with GO were prospectively compared with 40 eyes of 20-age and sex-matched controls. The severity and activity of the disease were evaluated according to the criteria of the European Group on Graves' Ophthalmopathy (EUGOGO) and Clinical Activity Score (CAS). After complete ophthalmologic and endocrinologic examination, all patients underwent optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) measurements. Retinal nerve fiber layer (RNFL) thickness, macular superficial capillary plexus (SCP), deep capillary plexus (DCP), foveal avascular zone (FAZ) area, acircularity index (AI) of the FAZ and peripapillary microvascular structure were analyzed.RESULTS:
The mean age was 12.1 ± 2.4 years in the GO group and 11.2 ± 2.6 years in healthy control group (p = 0.11). Duration of disease was 8.9 ± 4.2 months in the GO group. All patients in GO group had mild and inactive ophthalmopathy. In temporal inferior quadrant, RNFL thickness was significantly thinner in the GO group compared to the control group (p = 0.03). No significant difference was seen between groups both peripapillary and macular microvascular structure (all p > 0.05).CONCLUSION:
GO has no effect on optic nerve thickness, peripapillary and macular vascular parameters except inferior temporal RNFL in children.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tomografía de Coherencia Óptica
/
Oftalmopatía de Graves
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Child
/
Humans
Idioma:
En
Revista:
Int Ophthalmol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Turquía