Fecal microbial biomarkers in older adults with autoimmune diseases.
Future Microbiol
; 18: 949-957, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37477509
ABSTRACT
Aim:
To analyze the alterations in the fecal microbiota of older adults with autoimmune disease and determine the diagnostic capabilities of microbial biomarkers.Methods:
The raw data of fecal samples from 444 older adults from the publicly available American Gut Project database was analyzed.Results:
It was found that there were no significant differences in the microbiota richness and evenness between older adults with autoimmune disease and healthy controls. However, significant differences were observed in the microbiota composition and structure. The subject operating characteristic curve of the eight key microbiota was obtained, and the area under curve value was 70.0%.Conclusion:
Older adults with autoimmune disease showed changes in intestinal microbiota composition, which can be used as microbial biomarkers.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_zoonosis
Asunto principal:
Enfermedades Autoinmunes
/
Microbiota
/
Microbioma Gastrointestinal
Límite:
Aged
/
Humans
Idioma:
En
Revista:
Future Microbiol
Asunto de la revista:
MICROBIOLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China