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The safety and immunogenicity of a recombinant five-antigen Staphylococcus aureus vaccine among patients undergoing elective surgery for closed fractures: A randomized, double-blind, placebo-controlled, multicenter phase 2 clinical trial.
Jiang, Xie-Yuan; Gong, Mao-Qi; Zhang, Hua-Jie; Peng, A-Qin; Xie, Zhao; Sun, Dong; Liu, Lie; Zhou, Shuang-Quan; Chen, Hua; Yang, Xiao-Fei; Song, Jie-Fu; Yu, Bin; Jiang, Qing; Ma, Xiao; Gu, Jiang; Yang, Feng; Zeng, Hao; Zou, Quan-Ming.
Afiliación
  • Jiang XY; Department of Trauma and Orthopedics, Beijing Jishuitan Hospital, Beijing, China.
  • Gong MQ; Department of Trauma and Orthopedics, Beijing Jishuitan Hospital, Beijing, China.
  • Zhang HJ; DTaP and Toxins Division, National Institutes for Food and Drug Control, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, Beijing, China.
  • Peng AQ; Trauma Emergency Center of Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Xie Z; Orthopedic Department of Southwest Hospital, Army Medical University, Chongqing, China.
  • Sun D; Orthopedic Department of Southwest Hospital, Army Medical University, Chongqing, China.
  • Liu L; Orthopedic Department of the Eighth Affiliated Hospital, Sun Yat-sen University, Zhongshan, Guangdong, China; Orthopedic Department of West China Hospital of Sichuan University, Chengdu, Sichuan, China.
  • Zhou SQ; Chinese Osteo-traumatology Department of Shenyang Orthopedic Hospital, Shenyang, Liaoning, China.
  • Chen H; Department of Trauma and Orthopedics of the 2nd School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Yang XF; Orthopedic Department of Liaocheng People's Hospital, Liaocheng, Shandong, China.
  • Song JF; Orthopedic Department of Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
  • Yu B; Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, Chi
  • Jiang Q; State Key Laboratory of Pharmaceutical Biotechnology, Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China; Branch of National Clinical Resear
  • Ma X; DTaP and Toxins Division, National Institutes for Food and Drug Control, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, Beijing, China.
  • Gu J; National Engineering Research Center of Immunological, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing, China.
  • Yang F; Chengdu Olymvax Biopharmaceuticals Inc., Chengdu, Sichuan, China. Electronic address: yang.feng@olymvax.com.
  • Zeng H; National Engineering Research Center of Immunological, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing, China; State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China. Ele
  • Zou QM; National Engineering Research Center of Immunological, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing, China. Electronic address: qmzou2007@163.com.
Vaccine ; 41(38): 5562-5571, 2023 08 31.
Article en En | MEDLINE | ID: mdl-37516573
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Staphylococcus aureus / Fracturas Cerradas Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Vaccine Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Staphylococcus aureus / Fracturas Cerradas Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Vaccine Año: 2023 Tipo del documento: Article País de afiliación: China