Transcriptome-Wide Studies of RNA-Targeted Small Molecules Provide a Simple and Selective r(CUG)<sup>exp</sup> Degrader in Myotonic Dystrophy.

Gibaut, Quentin M R; Bush, Jessica A; Tong, Yuquan; Baisden, Jared T; Taghavi, Amirhossein; Olafson, Hailey; Yao, Xiyuan; Childs-Disney, Jessica L; Wang, Eric T; Disney, Matthew D

Transcriptome-Wide Studies of RNA-Targeted Small Molecules Provide a Simple and Selective r(CUG)^exp Degrader in Myotonic Dystrophy.

Gibaut, Quentin M R; Bush, Jessica A; Tong, Yuquan; Baisden, Jared T; Taghavi, Amirhossein; Olafson, Hailey; Yao, Xiyuan; Childs-Disney, Jessica L; Wang, Eric T; Disney, Matthew D.

Afiliación

Gibaut QMR; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Bush JA; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Tong Y; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Baisden JT; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Taghavi A; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Olafson H; Center for NeuroGenetics, University of Florida, Gainesville, Florida 32610, United States.
Yao X; Department of Molecular Genetics & Microbiology, College of Medicine, University of Florida, Gainesville, Florida 32610, United States.
Childs-Disney JL; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Wang ET; The Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States.
Disney MD; Center for NeuroGenetics, University of Florida, Gainesville, Florida 32610, United States.

ACS Cent Sci ; 9(7): 1342-1353, 2023 Jul 26.

Article en En | MEDLINE | ID: mdl-37521782

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Cent Sci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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