Full-field electroretinogram recorded with skin electrodes in 6- to 12-year-old children.
Doc Ophthalmol
; 147(3): 179-188, 2023 12.
Article
en En
| MEDLINE
| ID: mdl-37530953
ABSTRACT
PURPOSE:
To determine the full-field electroretinogram (ffERG) parameters, including the light-adapted (LA) 3 ERG and the photopic negative response (PhNR), in 6- to 12-year-old children.METHODS:
ffERG data were obtained from 214 eyes of 214 healthy subjects. The amplitudes and peak time of the ffERG responses were obtained from children divided into 6- to 8-year-old and 9- to 12-year-old groups. Using a skin electrode, electrical signals were measured in response to white stimulating light and white background light (LA 3 ERG). A blue background light and red flashes were then used to elicit the PhNR.RESULTS:
The a-wave amplitude ranged from 0.40 to 9.20 µV, the b-wave ranged from 4.70 to 30.80 µV, and the PhNR ranged from 1.30 to 39.90 µV. The b-wave peak time (33.20 ms) of 6- to 8-year-old groups was slightly shorter than that of the 9- to 12-year-old groups (33.60 ms, P = 0.01), but no differences in amplitudes or in peak time of other components. There were significant correlations between the amplitudes (a-wave and b-wave r = 0.43, p < 0.001; a-wave and PhNR r = 0.25, p < 0.001; b-wave and PhNR r = 0.45, p < 0.001). There was a moderate correlation between the a-wave and b-wave peak time (r = 0.31, P < 0.001).CONCLUSIONS:
We determined the largest dataset of the LA 3 ERG and PhNR parameters in a population of healthy children, aged 6-12 years, which may provide a useful reference value when evaluating children with potential retinal defects.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Células Ganglionares de la Retina
/
Electrorretinografía
Límite:
Child
/
Humans
Idioma:
En
Revista:
Doc Ophthalmol
Año:
2023
Tipo del documento:
Article
País de afiliación:
China