RSV replication modifies the XBP1s binding complex on the IRF1 upstream enhancer to potentiate the mucosal anti-viral response.

Qiao, Dianhua; Xu, Xiaofang; Zhang, Yueqing; Yang, Jun; Brasier, Allan R

Qiao, Dianhua; Xu, Xiaofang; Zhang, Yueqing; Yang, Jun; Brasier, Allan R.

Afiliación

Qiao D; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health (SMPH), Madison, WI, United States.
Xu X; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health (SMPH), Madison, WI, United States.
Zhang Y; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, United States.
Yang J; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, United States.
Brasier AR; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health (SMPH), Madison, WI, United States.

Front Immunol ; 14: 1197356, 2023.

Article en En | MEDLINE | ID: mdl-37564646

Asunto(s)

Endorribonucleasas; Infecciones por Virus Sincitial Respiratorio; Humanos; Endorribonucleasas/genética; Endorribonucleasas/metabolismo; Proteína 1 de Unión a la X-Box/genética; Proteína 1 de Unión a la X-Box/metabolismo; Proteínas Serina-Treonina Quinasas/genética; Proteínas Serina-Treonina Quinasas/metabolismo; Interferones/metabolismo; Inflamación; Factor 1 Regulador del Interferón/genética; Factor 1 Regulador del Interferón/metabolismo; Fosfatasas de Especificidad Dual/metabolismo; Fosfatasas de la Proteína Quinasa Activada por Mitógenos/metabolismo

Palabras clave

Cleavage Under Targets and Release Using Nuclease (CUT&RUN); X-box binding protein 1 (XBP1); innate immunity; inositol requiring enzyme (IRE1); interferon regulatory factor 1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Virus Sincitial Respiratorio / Endorribonucleasas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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