A portable liquid chromatography system based on a separation/detection chip module consisting of a replaceable ultraviolet-visible absorbance or contactless conductivity detection unit.
J Chromatogr A
; 1706: 464272, 2023 Sep 13.
Article
en En
| MEDLINE
| ID: mdl-37595418
ABSTRACT
Recently, there has been a growing demand for miniaturized analytical instruments, including portable HPLC systems, that can enable rapid analysis in the field. This study aimed to develop chip-based separation/detection modules with replaceable detection units for constructing compact HPLC systems to minimize the dead volume. This module provides a tubing-free connection between the column and the detection unit. This study also built detection units for conductivity detection and ultraviolet-visible (UV-Vis) detection to cover a wide variety of inorganic and organic compounds. Furthermore, UV- and Vis-light-emitting diodes were employed for the absorbance detection unit. In addition, portable all-in-one HPLC systems and a handy HPLC system were constructed for ion chromatography and reversed-phase chromatography, demonstrating the successful separation and detection of inorganic ions and several organic compounds.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromatografía de Fase Inversa
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Chromatogr A
Año:
2023
Tipo del documento:
Article