Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy.

Newell, Stella; van der Watt, Pauline J; Leaner, Virna D

Newell, Stella; van der Watt, Pauline J; Leaner, Virna D.

Afiliación

Newell S; Division of Medical Biochemistry and Structural Biology, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
van der Watt PJ; Division of Medical Biochemistry and Structural Biology, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Leaner VD; Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

IUBMB Life ; 76(1): 4-25, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37623925

Asunto(s)

Antineoplásicos; Neoplasias; Humanos; Transporte Activo de Núcleo Celular/fisiología; Proteína Exportina 1; Neoplasias/tratamiento farmacológico; Neoplasias/genética; Neoplasias/metabolismo; Carioferinas/genética; Carioferinas/metabolismo; Receptores Citoplasmáticos y Nucleares/genética; Receptores Citoplasmáticos y Nucleares/metabolismo; Antineoplásicos/farmacología; Antineoplásicos/uso terapéutico; Quimioterapia Combinada

Palabras clave

KPNB1; XPO1; cancer; combination therapy; nuclear transport proteins; targeted therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: IUBMB Life Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Sudáfrica

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