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Extensively drug-resistant Pseudomonas aeruginosa panophthalmitis from contaminated artificial tears.
Wang, Taylor; Jain, Sumeet; Glidai, Yoav; Dua, Prachi; Dempsey, Katharine S; Shakin, Eric; Chu, David S; Epstein, Marcia; Ha, Lawrence G.
Afiliación
  • Wang T; Dayton and Karen Brown Division of Infectious Diseases, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 400 Community Dr, Manhasset, NY 11030, USA.
  • Jain S; Department of Pharmacy, North Shore University Hospital, 300 Community Dr, Manhasset, NY 11030, USA.
  • Glidai Y; Department of Ophthalmology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 300 Community Dr, Manhasset, NY 11030, USA.
  • Dua P; Department of Ophthalmology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 300 Community Dr, Manhasset, NY 11030, USA.
  • Dempsey KS; Department of Ophthalmology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 300 Community Dr, Manhasset, NY 11030, USA.
  • Shakin E; Department of Ophthalmology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 300 Community Dr, Manhasset, NY 11030, USA.
  • Chu DS; Institute of Ophthalmology and Visual Science, New Jersey Medical School of Rutgers University, 90 Bergen St., Newark, NJ 07103, USA.
  • Epstein M; Metropolitan Eye Research and Surgery Institute, 540 Bergen Blvd., Palisades Park, NJ 07650, USA.
  • Ha LG; Dayton and Karen Brown Division of Infectious Diseases, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 400 Community Dr, Manhasset, NY 11030, USA.
IDCases ; 33: e01839, 2023.
Article en En | MEDLINE | ID: mdl-37645532
ABSTRACT
Pseudomonas aeruginosa is one of the common gram-negative organisms that cause severe invasive infections in different organ systems. P. aeruginosa has unique intrinsic mechanisms to develop antimicrobial resistance quickly, making it extremely difficult to treat. We report a case of extensively drug-resistant (XDR) P. aeruginosa panophthalmitis due to contaminated artificial tears. This report investigates the role of systemic and intravitreal antimicrobials, summarizes the resistance mechanisms of P. aeruginosa, and provides an overview on cefiderocol, a novel antimicrobial that targets multidrug-resistant (MDR) and XDR Gram-negative pathogens.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IDCases Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IDCases Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
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