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A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.
Taha, Taha Y; Suryawanshi, Rahul K; Chen, Irene P; Correy, Galen J; McCavitt-Malvido, Maria; O'Leary, Patrick C; Jogalekar, Manasi P; Diolaiti, Morgan E; Kimmerly, Gabriella R; Tsou, Chia-Lin; Gascon, Ronnie; Montano, Mauricio; Martinez-Sobrido, Luis; Krogan, Nevan J; Ashworth, Alan; Fraser, James S; Ott, Melanie.
Afiliación
  • Taha TY; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, United States of America.
  • Suryawanshi RK; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Chen IP; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, United States of America.
  • Correy GJ; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • McCavitt-Malvido M; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, United States of America.
  • O'Leary PC; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Jogalekar MP; Department of Medicine, University of California, San Francisco, California, United States of America.
  • Diolaiti ME; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Kimmerly GR; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, United States of America.
  • Tsou CL; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, United States of America.
  • Gascon R; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Montano M; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Martinez-Sobrido L; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States of America.
  • Krogan NJ; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States of America.
  • Fraser JS; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, United States of America.
  • Ott M; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States of America.
PLoS Pathog ; 19(8): e1011614, 2023 08.
Article en En | MEDLINE | ID: mdl-37651466
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicación Viral / Proteasas Similares a la Papaína de Coronavirus / SARS-CoV-2 Límite: Animals / Humans Idioma: En Revista: PLoS Pathog Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicación Viral / Proteasas Similares a la Papaína de Coronavirus / SARS-CoV-2 Límite: Animals / Humans Idioma: En Revista: PLoS Pathog Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos