Intratympanic dexamethasone in Manières disease and symptom control.
Acta Otolaryngol
; 143(8): 681-686, 2023 Aug.
Article
en En
| MEDLINE
| ID: mdl-37682583
ABSTRACT
BACKGROUND:
Manières disease (MD) is a chronic inner ear disease characterized by recurrent vertigo and fluctuation in auditory symptoms. Vertigo spells have a sudden onset and are difficult for patients to handle. Therefore, treating a patient with MD is still a challenge for clinicians.AIMS:
This study aims to analyse the short-term effects of intratympanic dexamethasone (ITD) on the various symptoms of unilateral MD. MATERIALS ANDMETHODS:
The study comprised 27 patients with unilateral MD and severe vertigo who failed medication therapy. Treatment was with ITD as an alternative to destructive therapy. Treatment is evaluated after four months.RESULTS:
Significant improvements were measured with Dizziness Handicap Inventory (DHI), Tinnitus Handicap Inventory (THI), frequency of vertigo attacks longer than 20 min, Functional Level Scale (FLS), and tinnitus sensation measured by the Analog Visual Scale (AVS). Patients with severe symptoms grading with DHI and THI experienced the most improvement. Patients have achieved substantial vertigo control in 73%.CONCLUSION:
ITD application shows improvement in controlling vertigo and tinnitus in patients under exacerbation in MD.SIGNIFICANCE:
It is a promising non-destructive addition to the 'stepwise treatment concept' in MD and can be used as a first-line treatment in vertigo control.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
Problema de salud:
1_doencas_nao_transmissiveis
Asunto principal:
Acúfeno
/
Enfermedades del Laberinto
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Acta Otolaryngol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Suecia