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Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms.
Pividori, Milton; Lu, Sumei; Li, Binglan; Su, Chun; Johnson, Matthew E; Wei, Wei-Qi; Feng, Qiping; Namjou, Bahram; Kiryluk, Krzysztof; Kullo, Iftikhar J; Luo, Yuan; Sullivan, Blair D; Voight, Benjamin F; Skarke, Carsten; Ritchie, Marylyn D; Grant, Struan F A; Greene, Casey S.
Afiliación
  • Pividori M; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Lu S; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
  • Li B; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Su C; Department of Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA.
  • Johnson ME; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Wei WQ; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Feng Q; Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Namjou B; Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Kiryluk K; Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
  • Kullo IJ; Department of Medicine, Division of Nephrology, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
  • Luo Y; Mayo Clinic, Rochester, MN, 55905, USA.
  • Sullivan BD; Northwestern University, Chicago, IL, 60611, USA.
  • Voight BF; Kahlert School of Computing, University of Utah, Salt Lake City, UT, 84112, USA.
  • Skarke C; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Ritchie MD; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Grant SFA; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Greene CS; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Nat Commun ; 14(1): 5562, 2023 09 09.
Article en En | MEDLINE | ID: mdl-37689782
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epistasis Genética / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epistasis Genética / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos