Matriptase-2 regulates iron homeostasis primarily by setting the basal levels of hepatic hepcidin expression through a nonproteolytic mechanism.

Enns, Caroline A; Weiskopf, Tyler; Zhang, Richard H; Wu, Jeffrey; Jue, Shall; Kawaguchi, Makiko; Kataoka, Hiroaki; Zhang, An-Sheng

Enns, Caroline A; Weiskopf, Tyler; Zhang, Richard H; Wu, Jeffrey; Jue, Shall; Kawaguchi, Makiko; Kataoka, Hiroaki; Zhang, An-Sheng.

Afiliación

Enns CA; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.
Weiskopf T; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.
Zhang RH; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.
Wu J; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.
Jue S; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.
Kawaguchi M; Faculty of Medicine, Section of Oncopathology and Regenerative Biology, Department of Pathology, University of Miyazaki, Miyazaki, Japan.
Kataoka H; Faculty of Medicine, Section of Oncopathology and Regenerative Biology, Department of Pathology, University of Miyazaki, Miyazaki, Japan.
Zhang AS; Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: zhanga@ohsu.edu.

J Biol Chem ; 299(10): 105238, 2023 Oct.

Article en En | MEDLINE | ID: mdl-37690687

Palabras clave

hai-2; hepatocyte; hepcidin; homeostasis; hormone; iron; matriptase-2; serine protease

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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