The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Zoonotic Avian Influenza and Mycobacterium tuberculosis.
Appl Biosaf
; 28(3): 135-151, 2023 Sep 01.
Article
en En
| MEDLINE
| ID: mdl-37736423
ABSTRACT
Introduction:
The Biosafety Research Road Map reviewed the scientific literature on a viral respiratory pathogen, avian influenza virus, and a bacterial respiratory pathogen, Mycobacterium tuberculosis. This project aims at identifying gaps in the data required to conduct evidence-based biorisk assessments, as described in Blacksell et al. One significant gap is the need for definitive data on M. tuberculosis sample aerosolization to guide the selection of engineering controls for diagnostic procedures.Methods:
The literature search focused on five areas routes of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination methods.Results:
The available data regarding biosafety knowledge gaps and existing evidence have been collated and presented in Tables 1 and 2. The guidance sources on the appropriate use of biosafety cabinets for specific procedures with M. tuberculosis require clarification. Detecting vulnerabilities in the biorisk assessment for respiratory pathogens is essential to improve and develop laboratory biosafety in local and national systems.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
/
2_ODS3
/
3_ND
Problema de salud:
1_medicamentos_vacinas_tecnologias
/
2_enfermedades_transmissibles
/
3_neglected_diseases
/
3_tuberculosis
Tipo de estudio:
Guideline
/
Prognostic_studies
Idioma:
En
Revista:
Appl Biosaf
Año:
2023
Tipo del documento:
Article
País de afiliación:
Tailandia