A Potential Role of NFIL3 in Atherosclerosis.
Curr Probl Cardiol
; 49(1 Pt B): 102096, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-37741601
ABSTRACT
Nuclear factor interleukin-3 (NFIL3), a proline- and acidic-residue-rich (PAR) bZIP transcription factor, is called the E4 binding protein 4 (E4BP4) as well, which is relevant to regulate the circadian rhythms and the viability of cells. More and more evidence has shown that NFIL3 is associated with different cardiovascular diseases. In recent years, it has been found that NFIL3 has significant functions in the progression of atherosclerosis (AS) via the regulation of inflammatory response, macrophage polarization, some immune cells and lipid metabolism. In this overview, we sum up the function of NFIL3 during the development of AS and offer meaningful views how to treat cardiovascular disease related to AS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Interleucina-3
/
Aterosclerosis
Límite:
Humans
Idioma:
En
Revista:
Curr Probl Cardiol
Año:
2024
Tipo del documento:
Article