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A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex.
Lee, Esak; Chan, Siu-Lung; Lee, Yang; Polacheck, William J; Kwak, Sukyoung; Wen, Aiyun; Nguyen, Duc-Huy T; Kutys, Matthew L; Alimperti, Stella; Kolarzyk, Anna M; Kwak, Tae Joon; Eyckmans, Jeroen; Bielenberg, Diane R; Chen, Hong; Chen, Christopher S.
Afiliación
  • Lee E; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
  • Chan SL; Department of Biomedical Engineering, Biological Design Center, Boston University, Boston, MA 02215.
  • Lee Y; Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
  • Polacheck WJ; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
  • Kwak S; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
  • Wen A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
  • Nguyen DT; Department of Biomedical Engineering, Biological Design Center, Boston University, Boston, MA 02215.
  • Kutys ML; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
  • Alimperti S; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
  • Kolarzyk AM; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
  • Kwak TJ; Department of Biomedical Engineering, Biological Design Center, Boston University, Boston, MA 02215.
  • Eyckmans J; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
  • Bielenberg DR; Department of Biomedical Engineering, Biological Design Center, Boston University, Boston, MA 02215.
  • Chen H; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
  • Chen CS; Department of Biomedical Engineering, Biological Design Center, Boston University, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 120(41): e2308941120, 2023 10 10.
Article en En | MEDLINE | ID: mdl-37782785
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasos Linfáticos / Quinasas Asociadas a rho / Molécula A de Adhesión de Unión / Linfedema Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasos Linfáticos / Quinasas Asociadas a rho / Molécula A de Adhesión de Unión / Linfedema Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article