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T7 expression plasmids for producing a recombinant human G1P[8] rotavirus comprising RIX4414 sequences of the RV1 (Rotarix , GSK) vaccine strain.
Philip, Asha A; Agbemabiese, Chantal A; Yi, Guanghui; Patton, John T.
Afiliación
  • Philip AA; Department of Biology, Indiana University Bloomington , Bloomington, Indiana, USA.
  • Agbemabiese CA; Department of Electron Microscopy and Histopathology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana , Accra, Ghana.
  • Yi G; Department of Biology, Indiana University Bloomington , Bloomington, Indiana, USA.
  • Patton JT; Department of Biology, Indiana University Bloomington , Bloomington, Indiana, USA.
Microbiol Resour Announc ; 12(11): e0060323, 2023 Nov 16.
Article en En | MEDLINE | ID: mdl-37819123
ABSTRACT
The live oral rotavirus RV1 (Rotarix) vaccine is formulated from the human G1P[8] RIX4414 virus. Based on RIX4414 sequences, T7 expression plasmids were constructed that supported recovery of recombinant RIX4414-like viruses by reverse genetics. These plasmids will advance the study of the RV1 vaccine, possibly allowing improvements to its efficacy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microbiol Resour Announc Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microbiol Resour Announc Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos