Polyubiquitin ligand-induced phase transitions are optimized by spacing between ubiquitin units.

Galagedera, Sarasi K K; Dao, Thuy P; Enos, Suzanne E; Chaudhuri, Antara; Schmit, Jeremy D; Castañeda, Carlos A

Galagedera, Sarasi K K; Dao, Thuy P; Enos, Suzanne E; Chaudhuri, Antara; Schmit, Jeremy D; Castañeda, Carlos A.

Afiliación

Galagedera SKK; Department of Biology, Syracuse University, Syracuse, NY 13244.
Dao TP; Department of Chemistry, Syracuse University, Syracuse, NY 13244.
Enos SE; Department of Biology, Syracuse University, Syracuse, NY 13244.
Chaudhuri A; Department of Chemistry, Syracuse University, Syracuse, NY 13244.
Schmit JD; Department of Biology, Syracuse University, Syracuse, NY 13244.
Castañeda CA; Department of Chemistry, Syracuse University, Syracuse, NY 13244.

Proc Natl Acad Sci U S A ; 120(42): e2306638120, 2023 10 17.

Article en En | MEDLINE | ID: mdl-37824531

Asunto(s)

Poliubiquitina; Ubiquitina; Ubiquitina/metabolismo; Poliubiquitina/metabolismo; Ligandos; Ubiquitinación; Sitios de Unión

Palabras clave

biomolecular condensates; ligand-induced phase transition; multicomponent phase separation; polyphasic linkage; polyubiquitin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ubiquitina / Poliubiquitina Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article

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