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Immunotherapy and biomarkers in patients with lung cancer with tuberculosis: Recent advances and future Directions.
Yang, Ling; Zhuang, Li; Ye, Zhaoyang; Li, Linsheng; Guan, Jingzhi; Gong, Wenping.
Afiliación
  • Yang L; Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Senior Department of Tuberculosis, Eighth Medical Center of PLA General Hospital, Beijing 100091, China.
  • Zhuang L; Hebei North University, Zhangjiakou, Hebei 075000, China.
  • Ye Z; Senior Department of Oncology, Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
  • Li L; Hebei North University, Zhangjiakou, Hebei 075000, China.
  • Guan J; Hebei North University, Zhangjiakou, Hebei 075000, China.
  • Gong W; Hebei North University, Zhangjiakou, Hebei 075000, China.
iScience ; 26(10): 107881, 2023 Oct 20.
Article en En | MEDLINE | ID: mdl-37841590
Lung cancer (LC) and tuberculosis (TB) are two major global public health problems, and the incidence of LC-TB is currently on the rise. Therefore effective clinical interventions are crucial for LC-TB. The aim of this review is to provide up-to-date information on the immunological profile and therapeutic biomarkers in patients with LC-TB. We discuss the immune mechanisms involved, including the immune checkpoints that play an important role in the treatment of patients with LC-TB. In addition, we explore the susceptibility of patients with LC to TB and summarise the latest research on LC-TB. Finally, we discuss future prospects in this field, including the identification of potential targets for immune intervention. In conclusion, this review provides important insights into the complex relationship between LC and TB and highlights new advances in the detection and treatment of both diseases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_tuberculosis Idioma: En Revista: IScience Año: 2023 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_tuberculosis Idioma: En Revista: IScience Año: 2023 Tipo del documento: Article País de afiliación: China
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