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DNA-encoded library-enabled discovery of proximity-inducing small molecules.
Mason, Jeremy W; Chow, Yuen Ting; Hudson, Liam; Tutter, Antonin; Michaud, Gregory; Westphal, Matthias V; Shu, Wei; Ma, Xiaolei; Tan, Zher Yin; Coley, Connor W; Clemons, Paul A; Bonazzi, Simone; Berst, Frédéric; Briner, Karin; Liu, Shuang; Zécri, Frédéric J; Schreiber, Stuart L.
Afiliación
  • Mason JW; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Chow YT; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Hudson L; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Tutter A; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Michaud G; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Westphal MV; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Shu W; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Ma X; Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Tan ZY; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Coley CW; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Clemons PA; Structural and Biophysical Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Bonazzi S; Structural and Biophysical Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Berst F; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Briner K; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Liu S; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Zécri FJ; Chemical Biology and Therapeutics Science, Broad Institute, Cambridge, MA, USA.
  • Schreiber SL; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
Nat Chem Biol ; 20(2): 170-179, 2024 Feb.
Article en En | MEDLINE | ID: mdl-37919549
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos