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Pharmacogenomic testing in oncology: a health system's approach to identify oncology provider perspectives.
Bhatt, Meghna; Peshkin, Beth N; Kazi, Sadaf; Schwartz, Marc D; Ashai, Nadia; Swain, Sandra M; Smith, D Max.
Afiliación
  • Bhatt M; MedStar Health, Columbia, MD 21044, USA.
  • Peshkin BN; Cancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.
  • Kazi S; MedStar Health, Columbia, MD 21044, USA.
  • Schwartz MD; National Center for Human Factors in Healthcare, MedStar Health Research Institute, Washington, DC 20008, USA.
  • Ashai N; Cancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.
  • Swain SM; MedStar Health, Columbia, MD 21044, USA.
  • Smith DM; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA.
Pharmacogenomics ; 24(16): 859-870, 2023 Nov.
Article en En | MEDLINE | ID: mdl-37942634
ABSTRACT

Aim:

Identify oncology healthcare providers' attitudes toward barriers to and use cases for pharmacogenomic (PGx) testing and implications for prescribing anticancer and supportive care medications. Materials &

methods:

A questionnaire was designed and disseminated to 71 practicing oncology providers across the MedStar Health System.

Results:

25 of 70 (36%) eligible oncology providers were included. 88% were aware of PGx testing and 72% believed PGx can improve care. Of providers who had ordered a medication with PGx implications in the past month, interest in PGx for anticancer (90-100%) and supportive care medications (>75%) was high. Providers with previous PGx education were more likely to have ordered a test (odds ratio 7.9; 95% CI 1.1-56; p = 0.0394).

Conclusion:

Oncology provider prescribing practices and interest in PGx suggest opportunities for implementation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Farmacogenética / Pruebas de Farmacogenómica Límite: Humans Idioma: En Revista: Pharmacogenomics Asunto de la revista: FARMACOLOGIA / GENETICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Farmacogenética / Pruebas de Farmacogenómica Límite: Humans Idioma: En Revista: Pharmacogenomics Asunto de la revista: FARMACOLOGIA / GENETICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
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