Potential of dental pulp stem cells and their products in promoting peripheral nerve regeneration and their future applications.
World J Stem Cells
; 15(10): 960-978, 2023 Oct 26.
Article
en En
| MEDLINE
| ID: mdl-37970238
ABSTRACT
Peripheral nerve injury (PNI) seriously affects people's quality of life. Stem cell therapy is considered a promising new option for the clinical treatment of PNI. Dental stem cells, particularly dental pulp stem cells (DPSCs), are adult pluripotent stem cells derived from the neuroectoderm. DPSCs have significant potential in the field of neural tissue engineering due to their numerous advantages, such as easy isolation, multidifferentiation potential, low immunogenicity, and low transplant rejection rate. DPSCs are extensively used in tissue engineering and regenerative medicine, including for the treatment of sciatic nerve injury, facial nerve injury, spinal cord injury, and other neurodegenerative diseases. This article reviews research related to DPSCs and their advantages in treating PNI, aiming to summarize the therapeutic potential of DPSCs for PNI and the underlying mechanisms and providing valuable guidance and a foundation for future research.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
World J Stem Cells
Año:
2023
Tipo del documento:
Article
País de afiliación:
China