Your browser doesn't support javascript.
loading
Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer.
Boutin, Rebecca; Lee, Hiu-Fung; Guan, Tian Lai; Nguyen, Tan Trieu; Huang, Xian Fang; Waller, Daniel D; Lu, Jordan; Christine Chio, Iok In; Michel, René P; Sebag, Michael; Tsantrizos, Youla S.
Afiliación
  • Boutin R; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Lee HF; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Guan TL; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Nguyen TT; Department of Biochemistry, McGill University, Montreal, Québec H3G 1Y6, Canada.
  • Huang XF; Department of Medicine, McGill University, Montreal, Québec H3A 1A1, Canada.
  • Waller DD; Department of Medicine, McGill University, Montreal, Québec H3A 1A1, Canada.
  • Lu J; Terry Fox Laboratory, BC Cancer Research Institute, Vancouver, British Columbia V5Z 1L3, Canada.
  • Christine Chio II; Institute for Cancer Genetics, Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Michel RP; Institute for Cancer Genetics, Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Sebag M; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Tsantrizos YS; Department of Pathology, McGill University, Montréal, Québec H3A 1A1, Canada.
J Med Chem ; 66(23): 15776-15800, 2023 12 14.
Article en En | MEDLINE | ID: mdl-37982711
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_colon_rectum_cancers / 6_endocrine_disorders / 6_lymphomas_multiple_myeloma / 6_pancreatic_cancer Asunto principal: Neoplasias Pancreáticas / Neoplasias Colorrectales / Carcinoma Ductal Pancreático / Mieloma Múltiple Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_colon_rectum_cancers / 6_endocrine_disorders / 6_lymphomas_multiple_myeloma / 6_pancreatic_cancer Asunto principal: Neoplasias Pancreáticas / Neoplasias Colorrectales / Carcinoma Ductal Pancreático / Mieloma Múltiple Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Canadá