Impact of HIV/HCV Co-Infection on Mortality and Attrition in Antiretroviral Therapy Among People with HIV - Guangxi Zhuang Autonomous Region, China, 2003-2022.

ABSTRACT

What is already known about this topic? The effects of concurrent human immunodeficiency virus (HIV)/hepatitis C virus (HCV) infection on mortality and patient attrition in those undergoing antiretroviral therapy continue to be a contested area of research. What is added by this report? According to the propensity score-matched cohort, individuals with HIV/HCV co-infection exhibit an elevated risk of all-cause mortality [adjusted hazard ratio 2.048, 95% confidence interval (CI) 1.526-2.749] and attrition (adjusted incidence rate ratio 1.659, 95% CI 1.4.8-1.961) compared to their counterparts who are mono-infected with HIV. What are the implications for public health practice? The pressing need for tailored testing and follow-up protocols for individuals co-infected with HIV/HCV cannot be overstated.