Development of a UPLC-MS/MS method for the determination of lacosamide and its metabolite and its application to drug-drug interaction.

Chen, Jie; Shen, Yuxin; Xia, Hailun; Chen, Xiaohai; Xu, Ren-Ai; Lin, Guanyang; Dai, Gexin

Chen, Jie; Shen, Yuxin; Xia, Hailun; Chen, Xiaohai; Xu, Ren-Ai; Lin, Guanyang; Dai, Gexin.

Afiliación

Chen J; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Shen Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xia H; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chen X; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xu RA; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lin G; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Dai G; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Front Pharmacol ; 14: 1265252, 2023.

Article en En | MEDLINE | ID: mdl-38026954

Palabras clave

UPLC-MS/MS; interaction; lacosamide; methodological verification; pharmacokinetic

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: China

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