An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA.

Stulz, Rouven; Lerche, Michael; Luige, Olivia; Taylor, Agnes; Geschwindner, Stefan; Ghidini, Alice

Stulz, Rouven; Lerche, Michael; Luige, Olivia; Taylor, Agnes; Geschwindner, Stefan; Ghidini, Alice.

Afiliación

Stulz R; Oligonucleotide Chemistry, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden.
Lerche M; Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden.
Luige O; Department of Biosciences and Nutrition, Karolinska Institutet, Neo Huddinge 14183 Sweden.
Taylor A; Early Chemical Development, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden.
Geschwindner S; Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden.
Ghidini A; Mechanistic and Structural Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden.

RSC Chem Biol ; 4(12): 1123-1130, 2023 Nov 29.

Article en En | MEDLINE | ID: mdl-38033730

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Chem Biol Año: 2023 Tipo del documento: Article