Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam.
Skinmed
; 21(6): 445-447, 2023.
Article
en En
| MEDLINE
| ID: mdl-38051248
ABSTRACT
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially fatal cutaneous hypersensitivity reaction commonly precipitated by antiepileptic drugs (AEDs). Cross-reactivity among aromatic AEDs is well-documented, but between aromatic and nonaromatic AEDs. We report a patient with severe DRESS syndrome precipitated by aromatic AED carbamazepine with recrudescence approximately 2 weeks after substitution with nonaromatic AED levetiracetam. The patient was treated with high-dose corticosteroids and switched to the benzodiazepine AED clobazam. At follow-up appointment several weeks later, the patient's rash, liver injury, and eosinophilia had resolved.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Eosinofilia
/
Síndrome de Hipersensibilidad a Medicamentos
Límite:
Humans
Idioma:
En
Revista:
Skinmed
Asunto de la revista:
DERMATOLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos