Highly sensitive determination of multiple pesticide residues in foods by supercritical fluid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry.
Food Res Int
; 175: 113769, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-38129060
ABSTRACT
This experiment aimed to establish a green, simple and highly sensitive method (supercritical fluid chromatography (SFC) coupled with ion mobility quadrupole time-of-flight mass spectrometry (IM-Q-TOF/MS)) for the detection of multiple pesticides in foods. During the experiments, several important SFC parameters, such as stationary phase, modifier, make-up solution, back-temperature and back-pressure were optimized. Here, single-field collision cross section (CCS) values and multifield CCS values of 20 pesticides were examined by IM-Q-TOF/MS as highly specific parameters with excellent experimental precision. In addition, based on accurate mass matching and fragment ion comparison, mass fragments were obtained by IM-Q-TOF/MS, which elucidated the regularities of compound structure and characteristic fragment ions. Under the optimized conditions, satisfactory linearity (R2 ≥ 0.9989) and recoveries (79.60 % to 112.97 %) were obtained. The intra- and interday precisions were favorable, with RSDs lower than 4.91 and 7.65 %, respectively. Additionally, the method showed low limits of detection (0.1-8.8 ng/mL). The proposed method has been successfully applied to the highly sensitive detection of phenylurea herbicide, triazine herbicides, organophosphorus pesticide, pyrethroid insecticide and acaricide in yam and potato.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plaguicidas
/
Residuos de Plaguicidas
/
Cromatografía con Fluido Supercrítico
Idioma:
En
Revista:
Food Res Int
Año:
2024
Tipo del documento:
Article