White Matter Injury on Early-versus-Term-Equivalent Age Brain MRI in Infants Born Preterm.
AJNR Am J Neuroradiol
; 45(2): 224-228, 2024 02 07.
Article
en En
| MEDLINE
| ID: mdl-38216303
ABSTRACT
BACKGROUND AND PURPOSE:
White matter injury in infants born preterm is associated with adverse neurodevelopmental outcomes, depending on the extent and location. White matter injury can be visualized with MR imaging in the initial weeks following preterm birth but is more commonly defined at term-equivalent-age MR imaging. Our aim was to see how white matter injury detection in MR imaging compares between the 2 time points. MATERIALS ANDMETHODS:
This study compared white matter injury on early brain MR imaging (30-34 weeks' postmenstrual age) with white matter injury assessment at term-equivalent (37-42 weeks) MR imaging, using 2 previously published and standardized scoring systems, in a cohort of 30 preterm infants born at <33 weeks' gestational age.RESULTS:
There was a strong association between the systematic assessments of white matter injury at the 2 time points (P = .007) and the global injury severity (P < .001).CONCLUSIONS:
Although the optimal timing to undertake neuroimaging in the preterm infant remains to be determined, both early (30-34 weeks) and term-equivalent MR imaging provide valuable information on white matter injury and the risk of associated sequelae.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lesiones Encefálicas
/
Nacimiento Prematuro
/
Sustancia Blanca
Límite:
Female
/
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
AJNR Am J Neuroradiol
Año:
2024
Tipo del documento:
Article