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The influence of orbital architecture on strabismus in craniosynostosis.
Lee, Tonya C; Walker, Evan; Ting, Michelle A; Bolar, Divya S; Koning, Jeffrey; Korn, Bobby S; Kikkawa, Don O; Granet, David; Robbins, Shira L; Alperin, Marianna; Engle, Elizabeth C; Liu, Catherine Y; Rudell, Jolene C.
Afiliación
  • Lee TC; Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Walker E; Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Ting MA; Division of Oculofacial Plastic and Reconstructive Surgery, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Bolar DS; Center for Functional Magnetic Resonance Imaging, Department of Radiology, University of California San Diego, La Jolla, California.
  • Koning J; Department of Radiology, Rady Children's Hospital, San Diego, California.
  • Korn BS; Division of Oculofacial Plastic and Reconstructive Surgery, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Kikkawa DO; Division of Oculofacial Plastic and Reconstructive Surgery, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Granet D; Division of Pediatric Ophthalmology and Strabismus, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Robbins SL; Division of Pediatric Ophthalmology and Strabismus, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Alperin M; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, California; Sanford Consortium for Regenerative Medicine, La Jolla, California.
  • Engle EC; Departments of Neurology and Ophthalmology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts; Howard Hughes Medical Institute, Chevy Chase, Maryland.
  • Liu CY; Division of Oculofacial Plastic and Reconstructive Surgery, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
  • Rudell JC; Division of Pediatric Ophthalmology and Strabismus, Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California. Electronic address: jrudell@health.ucsd.edu.
J AAPOS ; 28(1): 103812, 2024 02.
Article en En | MEDLINE | ID: mdl-38219920
ABSTRACT

PURPOSE:

To better characterize the correlation of bony orbital dysmorphology with strabismus in craniosynostosis.

METHODS:

The medical records of patients with craniosynostosis with and without strabismus seen at Rady Children's Hospital (San Diego, CA) from March 2020 to January 2022 were reviewed retrospectively in this masked, case-control study. Computed tomography scans of the orbits were analyzed to obtain dimensions of the orbital entrance and orbital cone. Primary outcome was correlation of strabismus with orbital measurements.

RESULTS:

A total of 30 orbits from 15 patients with strabismus and 15 controls were included. Craniofacial disorders included in the study were nonsyndromic craniosynostosis (63%), Crouzon syndrome (13%), Apert syndrome (13%), and Pfeiffer syndrome (10%). Orbital index (heightwidth ratio) (P = 0.01) and medial orbital wall angle (P = 0.04) were found to differ significantly between the strabismus and control groups.

CONCLUSIONS:

In our small cohort, bony orbital dimensions, including the ratio of orbital height to width and bowing of the medial orbital wall, were associated with strabismus in craniosynostosis.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acrocefalosindactilia / Estrabismo / Craneosinostosis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acrocefalosindactilia / Estrabismo / Craneosinostosis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2024 Tipo del documento: Article
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