Carriers of Heterozygous Loss-of-Function ACE Mutations Are at Risk for Alzheimer's Disease.

Danilov, Sergei M; Adzhubei, Ivan A; Kozuch, Alexander J; Petukhov, Pavel A; Popova, Isolda A; Choudhury, Ananyo; Sengupta, Dhriti; Dudek, Steven M

Danilov, Sergei M; Adzhubei, Ivan A; Kozuch, Alexander J; Petukhov, Pavel A; Popova, Isolda A; Choudhury, Ananyo; Sengupta, Dhriti; Dudek, Steven M.

Afiliación

Danilov SM; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Chicago, Chicago, IL 60612, USA.
Adzhubei IA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
Kozuch AJ; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Chicago, Chicago, IL 60612, USA.
Petukhov PA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA.
Popova IA; Toxicology Research Laboratory, University of Illinois Chicago, IL 60612, USA.
Choudhury A; Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg 2193, South Africa.
Sengupta D; Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg 2193, South Africa.
Dudek SM; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Chicago, Chicago, IL 60612, USA.

Biomedicines ; 12(1)2024 Jan 12.

Article en En | MEDLINE | ID: mdl-38255267

Palabras clave

angiotensin I-converting enzyme; conformational changes; mutations; plasma ACE; screening

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Biomedicines Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

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