New steroidal saponins from the aerial parts of Paris polyphylla var. yunnanensis and their effects on blood coagulation.
Fitoterapia
; 174: 105833, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38301935
ABSTRACT
Five new steroidal saponins, paripolins D-H (1-5), and 6 known compounds (6-11) were isolated from the aerial parts of Paris polyphylla var. yunnanensis. The structures of 1-5 were determined using spectroscopic analyses in conjunction with acid hydrolysis. It is for the first time to report the 12-hydroxysteroidal saponins from the genus Paris. The effect of all isolated compounds on blood coagulation was determined in vitro using the plasma recalcification time method. Compounds 1 and 2 showed potent procoagulant activity, and 5-11 exhibited significant anticoagulant activity.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saponinas
/
Liliaceae
Idioma:
En
Revista:
Fitoterapia
Año:
2024
Tipo del documento:
Article