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Lipidomic and proteomic profiling identifies the milk fat globule membrane composition of milk from cows and camels.
He, Jing; Si, Rendalai; Wang, Yulin; Ji, Rimutu; Ming, Liang.
Afiliación
  • He J; College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China; China- Mongolia Belt and Road Joint Laboratory on Biopolymer Applications, Hohhot 010018, China. Electronic address: hejing1409@163.com.
  • Si R; College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China; China- Mongolia Belt and Road Joint Laboratory on Biopolymer Applications, Hohhot 010018, China. Electronic address: sirendalai_imau@163.com.
  • Wang Y; College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China; China- Mongolia Belt and Road Joint Laboratory on Biopolymer Applications, Hohhot 010018, China.
  • Ji R; College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China; China- Mongolia Belt and Road Joint Laboratory on Biopolymer Applications, Hohhot 010018, China. Electronic address: yeluouto1999@vip.163.com.
  • Ming L; College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China; China- Mongolia Belt and Road Joint Laboratory on Biopolymer Applications, Hohhot 010018, China. Electronic address: bmlimau@163.com.
Food Res Int ; 179: 113816, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38342514
ABSTRACT
This study was designed to detect lipidomic and proteomic differences in the milk fat globule membrane (MFGM) fractions of cow and camel milk samples. In total, 353 lipid species were detected in these analyses, including 77 PEs, 30 PCs, 28 PIs, 59 SMs, 54 Cers, 13 LPCs, 14 LPEs, 20 PSs, and 4 PGs. These included 54 polar lipid species that differed significantly in abundance between cow and camel milk. Glycerophospholipid metabolism was identified as a core metabolic pathway associated with camel milk composition. Furthermore, 547 proteins exhibiting differential abundance were identified by a label-free proteomics methodology when comparing samples of MFGMfrom camels and cows. Of these proteins, those that differed most in expression between these groups were associated with metabolic pathways, including endoplasmic reticulum activity, endocytosis, and PI3K-Akt signaling. In conclusion, our findings provide a more thorough understanding of the composition of MFGM and its physiological significance, hence offering robust evidence for the potential utilization of camel milk as a nutritional resource in future developments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Camelus / Glicoproteínas / Gotas Lipídicas / Proteínas de la Leche Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Food Res Int Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Camelus / Glicoproteínas / Gotas Lipídicas / Proteínas de la Leche Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Food Res Int Año: 2024 Tipo del documento: Article
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