One nucleotide substitution in the 3'UTR generated the novel allele HLA-B*40:01:02:47 in a North Indian individual.

Sharma, Akanksha; Bagchi, Soumita; Barwad, Adarsh W; Agarwal, Sanjay Kumar; Kanga, Uma

Sharma, Akanksha; Bagchi, Soumita; Barwad, Adarsh W; Agarwal, Sanjay Kumar; Kanga, Uma.

Afiliación

Sharma A; Department of Transplant Immunology and Immunogenetics, Clinical Immunogenetics Laboratory, Centre for Excellence in Molecular Medicine (ICMR), All India Institute of Medical Sciences, New Delhi, India.
Bagchi S; Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Barwad AW; Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Agarwal SK; Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Kanga U; Department of Transplant Immunology and Immunogenetics, Clinical Immunogenetics Laboratory, Centre for Excellence in Molecular Medicine (ICMR), All India Institute of Medical Sciences, New Delhi, India.

HLA ; 103(2): e15377, 2024 Feb.

Article en En | MEDLINE | ID: mdl-38342777

ABSTRACT

ABSTRACT

HLA-B*40010247 differs from HLA-B*40010201 by one nucleotide change in the 3'UTR at position 2739 (A>T).

Asunto(s)

Antígenos HLA-B; Nucleótidos; Humanos; Regiones no Traducidas 3'; Alelos; Antígenos HLA-B/genética; Genes MHC Clase I; Secuenciación de Nucleótidos de Alto Rendimiento

Palabras clave

HLA-B; North India; next generation sequencing; novel allele

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos HLA-B / Nucleótidos Límite: Humans Idioma: En Revista: HLA Año: 2024 Tipo del documento: Article País de afiliación: India

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