Transforming research to improve therapies for trauma in the twenty-first century.
Crit Care
; 28(1): 45, 2024 02 13.
Article
en En
| MEDLINE
| ID: mdl-38350971
ABSTRACT
Improvements have been made in optimizing initial care of trauma patients, both in prehospital systems as well as in the emergency department, and these have also favorably affected longer term outcomes. However, as specific treatments for bleeding are largely lacking, many patients continue to die from hemorrhage. Also, major knowledge gaps remain on the impact of tissue injury on the host immune and coagulation response, which hampers the development of interventions to treat or prevent organ failure, thrombosis, infections or other complications of trauma. Thereby, trauma remains a challenge for intensivists. This review describes the most pressing research questions in trauma, as well as new approaches to trauma research, with the aim to bring improved therapies to the bedside within the twenty-first century.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Heridas y Lesiones
/
Servicios Médicos de Urgencia
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Crit Care
/
Crit. care
/
Critical care (London. Online)
Año:
2024
Tipo del documento:
Article
País de afiliación:
Países Bajos